﻿251
475611226014562117
ORIGINÁLNÍ3862207016996181224324367468561635735777
PRÁCE4677207016983165262348424
Ces38157936014570127174
Urol40147936014578115180208
2019;42477936014562121176229253
23(1):45257936014562122153208232254
43–5048047936014562119180239298
Obr.6243142013780149192216
1.871314201376287
Graf1014314801316698150178
závislosti12133148013151105152174210231286323355377
ušetřených1617314801315793139172203248305348394451
biopsií2095314801315679135192229249271
a23943148013156
nediagnostikovaných247731480131581051621842396243298013155111165201232253297350395448503546590645
signifikantních1289329801314060114169190214239283336392422477498543598
KP19093298013151103
na20343298013157111
PSA2166329801315299156
denzitě23443298013155101157199220251294
ve2659329801314791
skupině624344801313882137193215271318
pacientů9693448013156111157179225282312367
bez13633448013156103148
předchozí1538344801315687132188233289344386408
biopsie1973344801315679134190226247293
s22863448013146
negativní23593448013157104159214245267313370391
MRI6243598013183135157
(PIRADS801359801312979100152212279324
<11453598013166
3)1230359801315176
Fig.624374201375885149177
1.823374201376184
Lesions959374801314688125143197251286
with1264374801317696126180
a14643748013155
PIRADS1539374801315271123182248292
score1849374801313982133163206
<20743748013166
321593748013151
in2229374801312478
the2326374801313387131
first247737480131255180116146
biopsy26433748013155766243898013155109144187
group.831389801315685136191244261
The11123898013148104149
percentage12803898013156101131172214269298348402447
of1746389801315582
biopsies1847389801315677130184219237282318
that2184389801313387140170
would23733898013176129183203256
be26493898013156101
avoidedand624404801315598149169221265317385438491
the1128404801313285128
percentage1270404801315499127168209262290340392436
of1719404801315480
clinically181240480131456584137157199250269289331
significant2157404801313755107160180202227269319373401
cancers2571404801314596149624419801314688118154
that797419801313084137167
would9804198013176129183203256
be12534198013155101
missed13714198013187107141176220273
as1661419801315590
a17684198013155
function1842419801312681135179211231284339
of2198419801315581
PSA2296419801315297154
density24664198013156101155189208238284
Obr.29713142013778143184205
2.3192314201376190
Graf3334314801316594143168
závislosti3517314801314294138158191210262296326345
ušetřených3876314801315689132162191233287328370424
biopsií4314314801315575128182216234254
a45823148013155
nediagnostikovaných46513148013157101154174226279333385419297132980131325193144187238291332374427
signifikantních3412329801313856108161181203228270321374402456475518571
KP39973298013151101
na41123298013156108
PSAdenzitě4234329801315196151220263317357377406447
ve4695329801314688
skupině4797329801313778130183203256300
rebiopsií2971344801313274128149202256291310330
u33183448013156
pacientů33923448013155109153173217272300354
s37633448013138
negativní38193448013157101155208238257302357377
MRI42133448013183134155
(PIRADS438734480131287796148206272316
<47213448013165
3)4804344801315175
Fig.2971359201375886151180
2.3170359201376191
Lesions3316359801314690127147201257292
with3625359801317698128184
a38263598013155
PIRADS3898359801315373125185252297
score4213359801313882133164208
<44383598013166
345213598013151
in4592359801312075
the4687359801312985130
repeat4837359801312973128174229260
biopsy2971374801315577132187223267
group.3259374801315586138194248266
The35463748013149105151
percentage37183748013155102132175218274304356410456
of4195374801315582
biopsies4298374801315577131186222242288325
that4643374801313388142173
would48373748013176129184206260
be29713898013155101
avoided30883898013155100152174227272326
and34313898013154109163
the3613389801312984129
percentage37583898013155101131173216271300351405450
of4224389801315581
clinically432238980131456687141162206258279300344
significant4682389801313857111166186210235279331386415
cancers29714048013146100156202246277315
that3306404801313995150182
would35154048013176131187209264
be38064048013156103
missed39364048013188110145182227283
as4246404801315692
a43654048013156
function4441404801313592148194227249304361
of4829404801315583
PSA49324048013160107165
density29714198013155101157192212243290
Obr.6246742013778143184206
3.846674201376087
Graf984674801316594143169
závislosti1167674801314394138158191210262297326346
ušetřených1527674801315589132162190233287328370424
biopsií1965674801315575128182216235254
a22336748013155
nediagnostikovaných2302674801315710115417422727933338642062468980131325193144187238291332374427
signifikantních1065689801313856108161181203228270321374402456475518571
KP16506898013151101
na17656898013156108
PSAdenzitě1887689801315196151220263317357377406447
ve2348689801314688
skupině2450689801313778130183203256300
pacientů6247048013155109153173218272301354
bez9967048013155100144
předchozí1157704801315585128181225279332373393
biopsie1567704801315677130184219238282
s18677048013138
nálezem19227048013157110131175218261346
PIRADS2286704801315272123182248292
325957048013151
Fig.624719201375988153182
3.834719201376290
Lesions979719801314691128147202259294
with1298719801317899129185
a15087198013157
PIRADS1590719801315474126187255300
score1909719801314589141172216
of2151719801315683
322597198013152
in2331719801312984
the2435719801313894140
first260071980131265282119150
biopsy624734801315575128181215258
group.896734801315584135188241257
The11677348013148103147
percentage13287348013155100129170211265293343396440
of1782734801315580
biopsies1876734801315576128181216234278313
that2203734801313286138167
would23847348013175127180200253
be26507348013155100
avoidedand624749801315598149169221265317385438491
the1128749801313285128
percentage1270749801315499127168209262290340392436
of1719749801315480
clinically181274980131456584137157199250269289331
significant2157749801313755107160180202227269319373401
cancers2571749801314596149624764801314688118154
that797764801313084137167
would9807648013176129183203256
be12537648013155101
missed13717648013187107141176220273
as1661764801315590
a17687648013155
function1842764801312681135179211231284339
of2198764801315581
PSA2296764801315297154
density24667648013156101155189208238284
Obr.29826742013778143184205
4.3204674201376088
Graf3343674801316594143169
závislosti3526674801314394138158191210262296326346
ušetřených3886674801315588132162190232286327370423
biopsií4323674801315576128182216235255
a45926748013155
nediagnostikovaných46616748013156100153173226278332385419298268980131325193144187238291332374427
signifikantních3423689801313856108161181203228270321374402456475518571
KP40086898013151101
na41236898013156108
PSAdenzitě4245689801315196151220263317357377406447
ve4706689801314688
skupině4808689801313778130183203256300
rebiopsií2982704801313274128149202256291310330
u33297048013156
pacientů34037048013155109153173217272300354
s37747048013138
nálezem38307048013157110130175218261346
PIRADS4194704801315271123181247291
345037048013151
Fig.2982719201375885149177
4.3180719201376190
Lesions3322719801314688125143197251286
with3627719801317696125180
a38267198013155
PIRADS3900719801315372123182248292
score4211719801313881132162204
of4434719801315582
345357198013151
in4604719801312378
the4700719801313387132
repeat4850719801313275129174228257
biopsy2982734801315576129183217261
group.The3257734801315584135189243259301356400
percentage36727348013155100129171213267296346399444
of4130734801315581
biopsies4225734801315676129183218236281317
that4556734801313286139168
would47387348013176128182202255
be50077348013156101
avoidedand2982749801315598149169221265317385438491
the3486749801313285128
percentage3628749801315499127168209262290340392436
of4077749801315480
clinically417074980131456584137157199250269289331
significant4515749801313755107160180202227269319373401
cancers49297498013145961492982764801314688118154
that3155764801313084137167
would33387648013176129183203256
be36117648013155101
missed37297648013187107141176220273
as4019764801315590
a41267648013155
function4200764801312681135179211231284339
of4556764801315581
PSA4654764801315297154
density48247648013156101155189208238284