﻿634
1075582226014562116174
ORIGINÁLNÍ3862207016996181224324367468561635735777
PRÁCE4677207016983165262348424
Ces37067936014570127174
Urol39057936014578115180208
2020;41387936014562121178237261
24(2):44257936014561118151210240262
105–11247127936014562117176237290338390
Declaration624898013173132186211264299354390416478541
were1204898013182138174230
followed.1461898013141103130155218301358423445
All1934898013177103129
patients2090898013174128164190247310345391
were2520898013182138174230
informed624104801312381110168201291345406
about10531048013149110169228263
the1341104801313290144
surgical1510104801313996128187210259310333
procedure1867104801315993150200252313370403455
and23461048013149107167
reali‑2539104801313082131154177211
stic62411980131407699148
expectations7951198013153101162216267304354387410469528568
were13861198013178131163215
discussed1625119801315881121171229269310363424
with20721198013178102136195
all229011980131497295
the2411119801313189143
par‑25771198013160111143173
ticipants.624134801313458109133194246306340384406
Perioperative10561348013158110144169229291347381433467492543597
and16791348013152112174
postoperative18811348013161123165202260322378412464498523574628
risks,2536134801313459100147193214
as624149801315092
well7431498013179134159182
as952149801315192
potential10721498013160122156209270304328378403
complications15011498013150108200262287311361413447472532592634
of2162149801315889
the2277149801313595151
proce‑2455149801316095153205258295
dure6241648013160118151205
were8531648013179133166220
discussed1097164801316083124175234275317372434
before15551648013160116146205239292
the1873164801313392147
surgery.2046164801313998131190245278332347
Written24181648013190122146181220272332
informed624179801312486117179215311368433
consent10851798013162122185229286349385
was15081798013182136180
obtained17161798013171136173227252314372437
from2181179801314077138234
all2442179801316389114
the25841798013145108166
patients.6241948013161112146171225285319362384
Patients10321948013155105139163218278311355
were14121948013179133166220
fully1658194801312788112136185
informed1870194801312180110169203295350412
about23061948013150112173233268
our25991948013158118151
further624209801312990123163223278312
scientific962209801314091115170230264288319344395
and13832098013149109170
publishing15792098013160121182208231273332356416477
intentions,2083209801312281115169229263287347408449470
and25792098013149109171
gave6242248013160111161215
us8672248013158100
written9952248013179114139174213266326
informed1348224801312584114174208300355418
consent.17922248013151109170211267327361382
Surgery22002248013153112146206261295349
was25772248013179131173
performed6242398013161118151186246280373429491
by11422398013171121
one12892398013169131186
surgeon15022398013151110144204260321383
(PW).1911239801314096188223240
None21782398013181142203258
of24632398013169100
the25892398013145105161
patients6242548013161113147171226286320364
had10152548013164115176
any12182548013155115163
graft‑related1407254801316599151181221252287340365416450504566
issues,1999254801312870112170225268289
increased2314254801312888139172226276318373436
risk624269801313359101149
of8002698013170102
bleeding929269801317298155212276301362425
or13812698013170105
any15132698013162123172
other17132698013170105167223258
heath19982698013171127179214275
problems23012698013172107167231257313407449
compromising6242848013148105195255289346436459499522580640
the1289284801313291145
use1457284801315898152
of1632284801315888
STSG.17432848013150104155224245
Each20122848013150101151209
patient22452848013159110144167220279312
was25802848013179129170
fully624299801312990115139189
informed840299801313393123183217310366429
and12952998013160121183
educated15042998013164127186237290324378441
about19712998013160123184245281
all2278299801316185109
current24142998013159119153188242302336
trends624314801313468122182243285
in935314801313292
partial10533148013170123156195220270294
glans1374314801316993144204245
resurfacing1646314801314195138196230264317368391451513
surgery.21853148013150109142203258291345361
The25723148013161123178
realistic624329801313286136161185226262287337
expectations9883298013163113175232283322373408432492553594
were16193298013179133167221
discussed1866329801317094135186246287329385447
as23393298013160102
a24683298013160
part25543298013171123157196
of624344801316092
the7443448013146108165
informed937344801313597128190225321378443
consent.14083448013161121184227285347383405
Each18413448013163117170232
patient21013448013173128163189246308344
made24833448013193146210267
an6243598013150110
independent760359801313393154210271328388449504565599
decision,13853598013170125176200241265325386406
and18173598013160120182
opted20253598013168131166219281
for2333359801313898132
a24913598013160
less2577359801313489131173
invasive624374801312382130181223246296349
approach9973748013150111172206263315365424
regardless1446374801313184145195228287311365407448
the1920374801313291146
paucity20903748013160111169219243278330
of2444374801315888
data25563748013159110143194
on6243898013159120
Veriset7703898013166118152177218274309
use.11053898013169111166186
We13273898013191143
think14973898013144104128188236
that17603898013144104156190
the19763898013145105161
encouraging21633898013164124175233294327380442466526587
moment6244048013190151242298358392
was,10434048013180132173194
the1264404801313595150
knowledge,14404048013148110170251276331393455510529
that1995404801313596147181
the2202404801313595151
surgeon23794048013142101134194249310371
can6244198013149101161
still811419801314279103128152
perform9904198013161117151185244278370
redo1387419801313387150210
sugery16234198013142101163218251305
while19564198013179140164188243
using2227419801315899123183244
STSG.24984198013152106160229252
In774434801312383
total883434801313694128180205
we11154348013179134
performed12764348013161117151185244278371426488
617914348013154
procedures1873434801316195154205258321380413467510
in2409434801312484
525194348013155
pa‑26014348013161113149
tients624449801313458113173207251
who9084498013180141201
underwent11354498013166126188243276361415475509
partial16704498013168120154193217268292
glans1988449801316792143202244
excision22584498013161111160184225249308369
of2653449801316697
the624464801313494150
epithelium8004648013158120145180240296321344403494
and13214648013155114176
subepithelium15234648013146105167223285310345405461485509568659
followed2209464801313393118142202282337399
by26354648013165115
coverage6244798013149107157211245297358413
with10624798013180104140200
novel12874798013159119169223248
haemostatic15604798013159110165256316358395447481505556
material21404798013190141176229262287337362
–25264798013155
Ve‑26064798013156108144
risetTM6244948013132579815418980749540763082
.8924948013119
After774509801316492130181212
adequate10115098013157117170230287336368419
general14555098013167120178231263313335
anesthesia18145098013158116169209244302355395417465
induction,2303509801313189148205254290312370429447
the624524801313490142
patient7855248013160109140162213270301
was11055248013178127165
placed1289524801316083130178227286
in1599524801311875
a16935248013149
normal17615248013158115146235282304
supine2084524801314096154176232284
position.23875248013160118157177210231288345363
A6245398013164
tourniquet712539801314197155186245267326383436469
was12115398013180130169
placed1404539801316891139188239299
around1727539801315788145203260320
the2071539801314099152
base22475398013167117157210
of2481539801316593
the2598539801314199152
penis.6245548013160113171192230249
The8935548013151110162
plane1075554801316082130187240
was13345548013179128167
developed15215548013159111159210232290349402462
to2006554801313085
undermine21115548013158115174226257345367424476
the2610554801313087140
suspicious624569801314197137196218267288346404443
area1091569801315082133181
with12965698013179102135193
approximately15135698013150110170202259304327415464496547570618
521555698013153
mm22275698013191179
healthy24305698013159112160183216274320
margin6245848013190139171229251309
and9575848013158116176
only11575848013167125148196
few1377584801313790168
millimeters15785848013190112134156177266320353404436477
for2079584801313794127
benign22305848013169123181203262320
and25745848013159117176
premalignat624599801316193144233282304326385443491524
lesions1172599801312275115136194253292
respectively.1488599801313283123183237286322344394445468516529
Sharp20405998013151109158189250
dissection2313599801316081120160213263299321379437
between6246148013161116150233286340399
the10486148013142101155
subepithelial12286148013149107167222283306340399453476498547569
layer1822614801313281128181213
and20606148013158117178
the22626148013143102156
corpus24426148013158115147209268308
spongiosum6246298013141100159218277299357397453542
was11906298013180129169
performed.13836298013161115146178236268358411471490
After774644801316492130181212
complete10106448013151107196256279332365416
excision,14516448013154101148170209230288347365
the1840644801313593146
defect20126448013160113141193242278
was23166448013179129169
cove‑25096448013150106155206241
red624659801313284144
with7986598013179102135193
novel10156598013165123171223245
tissue1285659801313961100140196249
sealant15586598013147100148170219276308
VerisetTM18906598013162111142165204257290217266040763081
.22546598013119
Mild23036598013185108129189
com‑25166598013154110200233
pression624674801316192144184223245302360
on10056748013158116
the1145674801313188141
wet13066748013180132165
sponge14916748013141100159217276329
for1844674801312582114
a19786748013150
minimum20486748013190111169190279336424
of2493674801315886
1–225996748013154103150
minutes6246898013190111169225259309349
was9946898013179128168
applicated,11826898013150109169192213261310342393453471
before16736898013160114142199231282
releasing1979689801312880102155202242263320379
the2382689801313088141
tour‑2547689801313086143174203
niquet.624704801315981140197250283302
Afterwards,958704801316492130181212294344375433473491
a14737048013158
mild15637048013190112134193
compressive17807048013157113203263295346386426448497549
bandage23537048013168118176236284344397
with6247198013181104139198
fat847719801313890123
gauze9957198013169119178223276
and12967198013159119180
Baneocin15017198013164116175229290341363422
cream1948719801315991144193284
(combined2257719801313884142233295318377431493
antibacterial6247348013151110142165226277327364416448471521544
drug11927348013170102161222
for1439734801313796128
topical15927348013143100162185234285308
application,19257348013159120181205227277327360383442502521
which24797348013180140162212271
contains6247498013149106165197247269327367
two10157498013143125183
antibiotics12227498013159117149172232254313346368417459
with17137498013180103137195
bactericidal19337498013169119168205256288311360382442491513
effect,2471749801316291121173223260279
neomycin6247648013159112171261307354376434
and10827648013151109168
bacitracin)12757648013161111159181215246296345367424449
was17497648013180130169
applied19427648013151111171194216268329
after2295764801315179116167199
Foley25197648013151107130183231
catheter297689801314999131189242275326358
insertion335889801311977116169201238260318376
(Ch375889801312686143
12).392289801315498124140
The4082898013152112165
catheter426889801314998130189242275326357
was4646898013179129169
remo‑483989801312981170228263
ved29761048013150102162
after3162104801315785123174205
3/53391104801316198149
days35641048013167116162203
and37911048013157115174
patients39901048013168118150172224282314356
were43771048013180132163215
discharged4616104801316789128177235283315373425486
on29761198013159117
the3117119801313492145
third3286119801313492114145203
postoperative35131198013161120160195251311365396446478500550602
day.41391198013159108155168
On31261348013174133
the3283134801313492145
very34531348013150101133185
first366213480131275384125160
day38461348013160109155
after4026134801315078115166198
the4248134801313492145
surgery,4417134801314298130188241272324337
we47781348013180132
had49341348013159108168
removed2976149801313283171228276327386
the3386149801312987139
bandage35451498013160109166224272331383
and39481498013149106165
after4132149801315077114164195
careful4347149801314897128178206264286
inspection4656149801311976114173226275310332388446
of2976164801315987
the3087164801314199152
glans3263164801316688137195234
applied35211648013157116177200221274334
a38791648013157
new39601648013165118197
bandage41811648013167117175234283343395
with46071648013180102135193
a48251648013156
little490516480131305285121144197
bit2976179801316183117
less3117179801312073113153
compression.32911798013149105195254286338378418439497555574
On38871798013173132
the4043179801313190143
excision42071798013153101148170209230288346
site457717980131386093144
with47421798013180102136194
the4960179801313189142
remaining2976194801313284173222244301323380440
parts34361948013161111142179221
of3678194801315886
the3789194801313088141
Veriset39511948013156105136159198251284
material42561948013190139171222253276324346
we46231948013179131
applied47751948013150109170193214267327
a29762098013150
fat3050209801313484116
gauze31952098013160109166210262
with34852098013180102136194
Baneocin.37032098013160110168221280329351409428
Consequently41592098013163119178217270330387440498530552600
the4783209801313997150
Ve‑49572098013161110145
riset297622480131335696150184
material31922248013192141174226258281331353
was35782248013181131172
completetly37752248013157114205266290343377429463486535
resorbed4334224801314294135194227288343405
and47632248013159118178
fell4966224801313791114136
off2976239801315988118
within31162398013180102135193215273
3–534112398013154109160
days.35942398013160109155196215
Each38322398013151101149207
patient40622398013160110142165217275307
was43912398013180129169
followed4584239801312885108129187266318378
on49852398013158117
weekly29762548013180132187233257306
intervals3306254801313189121173204258308331370
thereafter37002548013142101154186238287315353404436
and41602548013158117177
carefully43612548013157108139191219279301323372
advised47572548013158118168191230284345
how29762698013159117195
to3196269801313995
proceed3321269801316193149199250303364
with37152698013179102135193
local3932269801312987136186208
wound41702698013180137195253312
management45122698013190139197246305358447500558590
(application2976284801312975135195219240289339371393451510
of3510284801316795
vaseline36292848013158108148201224246303357
mixed40182848013190112159211271
with43222848013179102135194
Baneocin45402848013164114172225284334356413
3×49782848013161124
daily,29762998013160109130152200213
after3212299801315078115166198
local3434299801312280129179201
hygiene36582998013159105163185238296349
with40292998013180102136194
aqua).42452998013150110167216241256
Within45242998013190114147205227284
a48312998013150
time4905299801313355143197
frame2976314801312963114204259
of3259314801316897
6–833813148013163122178
weeks35923148013180134188235280
the38963148013143102157
excised40773148013163111159182222276337
glans4439314801316992141200240
area4704314801315991144193
was49303148013180131172
completely29763298013150108201263287342376429453503
epithelialized35043298013163125149184244299323345395419441487541603
presumably41323298013171105158200258350401463487537
from4694329801313873131224
the49433298013144104159
healthy29763448013160114163186221280327
margins33363448013192142174233256315355
(Fig.3716344801313889111171191
1,3931344801316376
2).4031344801316390106
In4162344801313291
light4278344801313254114174206
of4509344801316897
this,46313448013143102125165184
once48733448013168128177229
the2976359801313492145
healing31433598013159112160183204262321
process3486359801316193149199250290330
was38383598013180129169
completed,40293598013149105195254277330363414475493
there4546359801313290143174226
was47943598013179129169
no49853598013159117
further2976374801312988119156214267299
wound32993748013179136194252311
care3635374801314998130181
required.3840374801313384144201223254306366385
RESULTS29784158018181157233330402468544
The31264498013153117175
mean33394498013193151203266
lesion3632449801313592137162224287
size3947449801315378126182
1441574498013166116
mm43124498013193187
(range4527449801314173127190254311
8–2248664498013166127178236
mm).29764648013192186214232
All32364648013176102126
the33904648013145107164
lesions3581464801313592135160222284327
affected3935464801316293129185239278333397
less4360464801313491135178
than45654648013146108160222
1/348154648013165100157
of50004648013170102
the2976479801313496152
whole31654798013181142204230286
glans3478479801317195147208250
surface.37554798013152112146181235287341360
The41424798013162126182
mean43614798013191148199260
follow-up46484798013139100126150211293329391454
was29764948013179131173
1031764948013160109
weeks33184948013179134190238284
(range3628494801313666118178240295
8–2439494948013161119169219
weeks).42004948013180134190238284311328
All4585494801317196120
patients47314948013167119154178233293327371
except29765098013153103153206268303
one33055098013169129185
were35265098013180134168221
free3774509801313974128184
of3984509801316999
primary41105098013171105130221272305359
local4496509801313393145197222
disease.4744509801317094135191241283338358
In2976524801312383
one30875248013159120175
case32885248013151103145200
of3517524801315889
well36345248013179134159183
differentiated3845524801316084114149203237291351385409460494547610
intraepithelial4481524801312585119153205260322346382442497522546596621
neoplasia29765398013159115176239264315357381432
(PeIN),3434539801314096149174245276293
the37545398013144105160
final3941539801313964124176200
histology4168539801316993134171230255316378429
confirmed46245398013159117178208234268360416478
(PeIN)2976554801312986139164235266
crossing3268554801316093153195237261321383
into3677554801313494128187
squamous39255548013151113173224316376437479
cell44305548013160113138162
carcinoma46195548013159111145194218279339432483
(G1R+,32976569801312996145195260273329
mm).33395698013190181208225
The35915698013158120176
patient37935698013168120155179234294328
underwent41475698013166126188243276361415475509
a46825698013158
second47665698013149104156214275336
glans-preserving2976584801316085136197239272336371425468523557613638699761
procedure37645848013171106165217271334393427481
followed4272584801313999125149210291346409
with47185848013180105141201
Ve‑49465848013167119156
riset297659980131335799154190
application.31925998013161123185211235285337372396457517539
The37575998013162124180
frozen3963599801313974133178232292
section42825998013151107159197222282343
as46515998013161103
well47905998013180135160184
as50005998013160103
final2976614801312955116168193
histology3196614801317195137175234260321385437
demonstrated36956148013171127220282344386424458512547601665
no43876148013170131
evidence45456148013165117143205261323375429
of50016148013169101
PeIN29766298013155108133204
nor32086298013159120154
SCC.33886298013154118178199
For31266448013151109143
the3295644801313292146
remaining3467644801313184175225249308332391452
cases39436448013149101142197239
the4208644801313292146
histology4379644801315882123159217242301363413
confir‑48176448013149106166196221254285
med29766598013189144205
chronic32286598013147106139196256279329
balanoposthitis35806598013161112135185244304365425467503562585620643684
(24289659801312780
pts)4393659801316094137163
and45806598013149108169
verruca47726598013150103136169229279330
vulgaris29766748013149109133194245278302343
(penile3345674801312789144204227251306
horn,36756748013158118152212232
239316748013154
pts),4009674801316095138165182
what42156748013179139190224
was44636748013179130172
in4661674801312180
correla‑47656748013149106140174227252302337
tion2976689801313457116175
with31756898013178102137196
the3397689801313190145
primary3565689801316093118207257289342
preoperative3931689801316093146206267322355406439463513566
biopsy4521689801316084143204245295
result.4842689801313083124182205240260
In2976704801312383
both30857048013169131165226
patients33377048013169121156180235295329373
with37447048013180104140200
PeIN39707048013164117141213
and42097048013158118180
one44157048013167128183
balanopo‑46247048013169121146197257317379441478
sthitis2976719801314179140164200225266
case32697198013160112155211
we35177198013180135
performed36797198013171128162197257292385441504
circumcision4210719801316084118167228320371396437461522583
in4820719801313394
the49417198013144105161
same2976734801314295188245
setting.32487348013152108144184209270333354
All36297348013176102126
benign37827348013172130191216278339
lesions4148734801313591134158220282324
were45107348013180136170225
treated4762734801314580135186221276340
with29767498013181107144205
various32097498013161115149175237299342
topical35787498013145105169195247301326
regimens3931749801314499164189282339401444
previously,44027498013173108163216242303365408433485501
ho‑49307498013171133172
wever29767648013179134185239272
without32777648013179104140200260320356
any36597648013153113161
success.38467648013143102153201254297339361