619
114202226014562110163
ORIGINÁLNÍ852207016996181224324367468561635735777
PRÁCE1667207016983165262348424
Ces8507936014570127174
Urol10497936014578115180208
2020;12827936014562121178237261
24(2):15697936014561118151210240262
113–12518567936014562110162222276327387
entů850898013153109140196
nebyla1065898013158110168214236284
biopsie136889801315981137196235256307
opakována1694898013157116165209265312360416464
(došlo218189801312579136175196252
k2452898013146
celkovému251789801314998120164219266316404459
zhoršení8501048013144103161193234287345366
stavu1240104801314781131179237
(n1501104801313589
=16201048013166
6),1710104801315985101
re‑biopsie1835104801313889124185207265325365386439
byla23031048013161108132180
pacientem25131048013160110159181233291323374463
odmítnuta8501198013159119208230263321378412461
(n1335119801313691
=14561198013166
2),1546119801316086102
netrvalo16721198013166119152183236286308366
ji2062119801313052
klinické218211980131537798156178226271323
podezření25291198013167126187240284316367425447
z8501348013144
nádorového9141348013159108167224256312360412470528
posti14621348013160119159193215
ení17181348013153111132
(n1874134801312680
=19741348013166
4)2060134801315378
nebo21581348013159112171230
byl24081348013161108131
indikován2563134801311976135157202258306356413
chirurgický8501498013149107128160218249307329377422474
výkon,13481498013150102148205264282
kdy16541498013146104152
histologické1830149801315981120154210234292352374422467519
vyšetření23731498013149101142195228259311369390
bylo27871498013161108131189
provedeno850164801316294152202255316370429489
v13631648013159
rámci1447164801314192183233255
vyšetření17271648013159112153207241273326385407
preparátu21591648013170103156216267300351384443
(n2626164801313894
=27531648013167
6)).2845164801316289115130
Nejzáva8501798013170123145188239286335
nější12291798013159111133172193
komplikací14421798013146103192251274296341391439461
byl19231798013161107131
perirenální20741798013160114145167198250307356378435456
hematom25501798013159112201249281337426
s8501948013141
nutností9151948013159116150208266306341363
podání13021948013161120180229287308
krevní1634194801314780132181240261
transfuze1919194801313466116174213243302346397
(Clavien2340194801312989111160207230282340
2).270419480131548095
Závěr:10002096013361117170225263289
Biopsie1323209801315680140202244268323
tumoru16722098013143103194255289349
ledviny2048209801313287149201226286334
je2408209801313388
bezpečná25222098013170126173235292343403454
a8502248013150
spolehlivá9262248013145106167193248308332356407459
diagnostická1415224801316084134196256316359395420470518571
metoda.20152248013190146181239302353374
V24152248013159
námi25012248013162113204228
hod‑27552248013162123185221
noceném8502398013159119171224284340431
souboru13072398013148109169231292326387
byla17202398013168118143194
BTL19402398013163116168
v21342398013157
naprosté22182398013166117179213272314351404
většině26482398013157111146190213273328
prováděna850254801316093150199250310363422471
pod13452548013159119180
CT15492548013161117
kontrolou.16912548013144101160193226283308366425445
Nejčastější21592548013169123147196246287322374397437459
indikací2644254801312078139162208259309332
byla8502698013161110136187
histologická1063269801316993134171229255315378402452500553
verifikace16422698013160114148173204229277330381434
před21022698013171105159221
onkologickou23502698013168129177236261322384408459506565626
léčbou850284801312378130191253313
u11872848013159
metastatického12712848013190145180232274311362397421471519573633693
onemocnění19892848013159119175266326378438493553577
a25912848013149
převlá‑2665284801316195148199225275311
dajícím8502998013159109133156206229319
histologickým1192299801315982122158216240299361384434481533624
nálezem18402998013159109132187232285375
byl22392998013160109133
světlobuněč‑2398299801313990143178202261322382441495545578
ný8503148013159107
renální983314801313589149200224284308
karcinom.13173148013149102135184208268328420441
KLÍČOVÁ8523434014770132164236320392464
SLOVA13433434014762123207279351
Biopsie,850359801315678135196236257310326
diagnóza,1200359801316082130190247306348399417
histologie,1641359801315981120154210233291352373426443
karcinom,2108359801314697128175197254313402420
ledvina.2553359801312376136185208266314334
SUMMARY8523884014762143243345423493561
Kolář10004048013154109130176205
J,1222404801313753
Pitra1291404801315574105135182
T,1490404801315161
Pivovarčíková1567404801315574121175221269298342362407462508555
K,2139404801315474
Trávníček2230404801315073120166222242287336379
I,2631404801311834
Lepič2682404801314998155176222
F,2921404801315055
Hes8504198013170122161
O,1041419801317489
Hora11604198013170127158207
M.13974198013186106
Renal15264198013163115172220241
tumor1790419801314198187244275
biopsy2095419801316183140199238287
–24054198013162
indications,2490419801313187146167214263294316372430469486
technique,850434801313484132189245266324380432447
results.1320434801313282121177198230270289
Aim:1000449601336791181201
To12264498013151101
evaluate13514498013154101150171227275306356
kidney1730449801314770128185237283
biopsies2038449801316082138197236257308347
performed24094498013161114144175231262351403462
at2896449801315081
our8504648013159115146
department10174648013160111170219249285373425482513
and15514648013150107165
to1739464801313287
compare18484648013149103192250299329380
the2251464801313289141
data24134648013160108139187
with26224648013179101133190
the2835464801313289141
literature.85047980131234476126156205236293323373389
Material10004946013388140174226261285336360
andmethods:13774946013353112173281335370429488549591611
A20064948013164
retrospective2093494801312878110140195234292344393427448496547
analysis26584948013149106153174221260280318
of850509801315885
patients9525098013161109139160210266297337
who13065098013179135192
underwent15155098013158114172223253333383439469
renal2007509801312777133180200
tumor2230509801312884171228258
biopsy2505509801316182137196234282
dur‑28045098013160115144172
ing850524801312379138
the1011524801313390142
years11745248013149100147177217
2007–2019.14125248013154105159207254300351397441455
Results:10005396013359113155213237272315335
During13545398013171128158180236294
the1671539801313086138
time1832539801312950138190
period20405398013161113144165222281
I/2017–XII/2019,2344539801311855107158204247294349369390427479530576620633
we8505548013179130
performed10035548013161114144175231262351403462
renal1488554801313283139187208
tumor1719554801313490178236266
biopsy2008554801316182139198237285
on23165548013158116
20024545548013154105158
patients26355548013161110141162213270301341
at850569801315080
our9485698013158114143
department11095698013159110168216246281369420476506
–16335698013154
128men1705569801315396145252303359
(64.02087569801312472126142194
%)22985698013181104
and24205698013149105163
7226005698013154104
wom‑27215698013179135222255
en8505848013154112
(36.0985584801313787139157210
%).12265848013182106121
The13705848013159119171
average15655848013157105156187237296348
age19375848013157117169
of2130584801316694
the22475848013142100152
patients24305848013161111142164216274305346
was28075848013180130169
64.88505998013154108125178
years10515998013149100146177216
(34–851290599801313079132188242292
years).1605599801314899146176216240254
Most18815998013186143182216
of2120599801315885
the2228599801313491143
biopsies2394599801316182139198237257309348
were27655998013179130160211
performed8506148013162116147179236268359412473
under13466148013167125185238269
CT16466148013163118
guidance17886148013168125147206255313362412
(n2224614801313792
=23476148013167
192;24386148013161106156173
96.026356148013162116135188
%),28546148013182107122
a8506298013150
minority9286298013191111168225256277309360
of1316629801315986
the1425629801313996148
biopsies1602629801316182139198237257308348
performed19786298013161114144175231262351403462
under24686298013159116174226256
ultra‑2752629801315980112143191224
sonography850644801314198155212271300349407464509
guidance13776448013160115136194241297345394
(n1794644801312478
=18906448013165
8;1973644801315369
4.02060644801315470122
%).22006448013181105119
The23376448013151109161
most25166448013190146185218
com‑27526448013149104192224
mon8506598013192151210
indication1083659801313189149171219269301323381440
for1547659801313794126
the16976598013142101154
kidney1875659801315578138196250297
biopsy2196659801316992150211251300
was25286598013180130170
histo‑2722659801316889128163219254
logical850674801312380139160207256277
verification11496748013150101131152177204251300331352408466
in1638674801312278
metastatic17396748013190142174222261294343374395442
disease2203674801316081119171218256308
before25336748013161114141197228278
the2834674801313390142
beginning8506898013161114173194250307327384442
of1311689801315986
oncologic14176898013158116163218240297356377424
treatment1864689801313061111158189278330387417
(n2304689801312680
=24036898013166
162;2488689801315499149165
81.026736898013153100111164
%),28566898013181105120
the850704801313389140
histological1007704801315878114147200221277335355401448468
verification1492704801314999128149173199245292322342398454
of1963704801315784
unclear20647048013157113159179229275304
lesions2390704801311869107126181237274
(n2687704801312376
=27797048013165
32;28617048013153100115
16.08507198013154101120173
%)10547198013182107
and11847198013158116175
biopsy1383719801316991149209249298
prior17057198013168100122180212
to1940719801314298
radiofrequency2062719801314090149171228256289340401458511569617668
abla‑27547198013158117140188222
tion850734801313456113172
(n1045734801313792
=11677348013167
6;1257734801316278
3.01359734801316178132
%).15217348013182107121
The16667348013159119171
initial1861734801313088109142163211233
biopsies2118734801316890148208248268321360
were25097348013181132163215
diag‑2747734801316889137196229
nostic8507498013161120160195218267
in1141749801313190
16512557498013162110162
cases14417498013158109149203244
(82.51709749801313789141158213
%).19547498013183108123
The21017498013160121175
most23087498013193152193228
common25607498013158115206297357416
histological850764801315980117151206228285344365412460481
findings1357764801312653109168188245303341
were17237648013180131161212
clear1958764801315172124171201
cell21827648013151101122143
renal2348764801313585142189211
cell25827648013151101122143
carci‑27487648013151100130175196228
noma3203898013158115202249
(n347489801312477
=3568898013165
107;365089801315398146157
53.53824898013153101117169
%),4010898013180104118
papillary4145898013160108165186207227273303352
renal452089801312776132179200
cell473789801314897118138
carcinoma489289801314997126171191246303390437
(n3203104801312983
=33141048013165
19;34021048013159103120
9.53545104801315973125
%),36981048013181105120
urothelial3846104801315888144175232284305326373394
carcinoma42631048013154103133178199256313401449
(n4735104801313488
=48511048013165
15;49391048013159103116
7.55078104801315965117
%)52231048013181105
and32031198013149104161
chromophobe33801198013149103132186272328385441497554606
renal4007119801312776131177197
cell4221119801314896117136
carcinoma4374119801314895124168188243298384431
(n4827119801312375
=49191198013164
3;5000119801315266
1.55083119801315363114
%).52141198013179102115
The32031348013152113167
remainder3394134801314093183232254312373426458
of3876134801316796
histological3996134801316789128163220243301363384433483506
findings4526134801313462120180202260320360
were49171348013181134166218
col‑51591348013157114137170
lected3203149801312477127163215276
from3503149801313669126217
2137441498013162110
patients38781498013169119152174227285317359
(10.54261149801313785132150204
%).44961498013183108123
Non-diagnostic46501498013172131190224286308356416475534574608630679
were32031648013179130160210
3534311648013154102
histological3551164801315980117151205227284343363410459480
samples4049164801314089177235257308347
(17.54419164801312471113119171
%);46081648013181105120
re-biopsy4751164801312777111171192248307346394
was51631648013179128166
performed32031798013161113144174230261350401460
in3686179801311875
173779179801315396
cases3893179801314997136188227
fromwhich4142179801312456111200297354375422478
164638179801315499
were47551798013180130161211
positive.49841798013161118157177209230278329345
In3203194801312378
the3303194801312884134
remaining3460194801312675161208228283302357414
183891194801315397
cases4005194801314896133184222
biopsy4243194801316081136194231278
was45381948013178126163
not47181948013158114144
performed48791948013160111140170225255342392450
again32032098013150108156177233
(due3459209801313691147199
to3681209801314196
the3800209801314198150
deterioration39792098013160112144194224246303334382414435491549
of4551209801316592
patient's46732098013161110141162213270301320357
health50532098013166118165186219276
(n3203224801312983
=33132248013165
6),340122480131588398
due35262248013160116167
to3716224801313893
re-biopsy3832224801313787120180202258318357405
being42642248013160113134190249
refused4536224801313687114171210262321
by48842248013160106
the5013224801313895147
pa‑51872248013161110142
tient3203239801313456108166198
(n3424239801313792
=35472398013166
2),3637239801316187102
due37622398013168125178
to3964239801314197
the4085239801314199152
absence42612398013158117157210268316367
of4652239801316694
suspicion47702398013148105144203225273294352410
for5204239801313693125
the3203254801313593146
malignant33812548013191140162184243301350408440
tumor38452548013142100190249280
(n4149254801313793
=42732548013166
4)4363254801316287
and44742548013158116176
finally,4674254801313562120169191212260273
649712548013162
of5056254801316796
the51752548013142101154
patients32032698013160107137157207262291331
underwent35502698013158113169220249328377433462
surgery4029269801314094123178228257307
and43522698013149104161
had45302698013158104161
the4707269801313489139
histological4863269801315878114146200221276333353399446466
examination32032848013153100148236257313361392413470527
performed37562848013160113143174230261350402461
from4240284801313264119208
the4471284801313693145
removed4639284801313585173231278329388
tissue).505028480131365795134189241265279
The32032998013151110162
most33922998013190147186219
serious3634299801314597127149205262300
complication39572998013153108196255277297344393424445502559
was45432998013179128166
in4732299801312783
the4838299801313895147
form5008299801313288119208
of5243299801315886
perirenal32033148013161113143165195245302349370
hematoma35913148013159111198246277331420467
which40763148013180137157204261
required4359314801312878137193213243294353
blood4730314801316082139196255
transfu‑5008314801312960108165203231289321
sion3203329801314161118175
(Clavien3401329801312887108155202223275332
2).375432980131547993
Conclusion:33533446013364121181229253311353377436495515
At3888344801316495
our40023448013159115146
department,41673448013160112170219249285373426482513531
we47173448013180131
performed48673448013161114144175231262351403462
the3203359801313593146
biopsy3373359801316991149209249299
of3695359801316795
the38143598013142100153
kidney3991359801315578138196249296
on43113598013167126
20044603598013162114169
patients46533598013169119151173225283315357
during50333598013168126157179237296
2007–2019,32033748013154104158206254300350397441454
under36803748013158115173225255
CT39583748013163116
guidance40973748013160116137195243299347397
in4517374801312379
the4619374801313491143
vast4785374801315098137170
majority49783748013190138159216247268301351
of3203389801315986
cases.33123898013153102140192232250
The35853898013155114166
most37783898013191148187220
common40213898013153108197285342399
indication4443389801312884142163210259290311368425
was48953898013180128167
histo‑5089389801315980118151206240
logical3203404801312379137157204252272
verification34924048013150100129150174201247295325346401458
preceding3967404801316191140188237295315371428
oncological44124048013158115162215237293351371418465486
treatment4920404801312959108155185272323379409
and32034198013150107165
the3391419801313289141
most35544198013190147186219
common37954198013149103192280337394
finding4211419801312653109168189245303
was45364198013179128166
clear4724419801314970121168198
renal4945419801313182138186207
car‑5174419801314997127155
cinoma.3203434801314970126183272320338
KEY32044634014770134206
WORDS343746340147105189260345408
Biopsy,3203479801315678135196236285298
carcinoma,3525479801314999130177199256314404453471
diagnosis,4020479801316082130190248306346367406425
histology,4469479801315980119154210233291351400413
kidney.4906479801314670129187240288301
………320349340147120235350
ÚVOD32055358018197183286388
V33535698013157
roce3435569801314199149201
201836615698013163115164211
zemřelo38975698013154106197229281304364
v42855698013159
souvislosti43695698013150109168219242282305364405440463
s48575698013150
renálním4932569801314193152202225284306397
karcinomem32035848013148101135184208268329422478571
(RCC38005848013144101166227
–40535848013170
Renal41495848013170126187238262
Cell44375848013178132156180
Carcinoma)46435848013178130163213236297358451503530
asi51995848013165107130
1753203599801315497147
00033635998013154109164
lidí,3551599801312142101123141
co37135998013149105
RCC38855998013153115173
zařadilo4079599801314495126176235257279337
na44375998013159108
16.45665998013154101120
místo47075998013190112151185241
v49695998013150
ebříč‑50435998013193153185207255286
ku32036148013147105
úmrtí33316148013158147179216238
asociovaných3592614801315090148198219277325375433479526584
s42006148013141
nádorem.42646148013159108167225257309398417
Celosvětově47046148013163114137195235285337369425474525
je5253614801312376
RCC32036298013156118176
6.3405629801315473
nejčastější35056298013159112134182231271306356378417438
nádorové39706298013159108167225257314362414
onemocnění44116298013158117170259317367425478535557
u49956298013158
mu50806298013190147
ů52716298013158
a32036448013150
10.32776448013157104122
u34276448013158
en35096448013199157
(1).3690644801313381101116
Navzdory38346448013170119166213271329361413
pokrokům42746448013161120166200256303360449
v47476448013153
diagnostice4828644801316082130189247305345380402450501
a32036598013150
léčbě3277659801312477126186239
nádorů35416598013159108168226258316
ledvin3881659801312477137186209267
mortalita41736598013190148180217267289311344394
u45926598013158
karcinomu4674659801314798130176198256314403461
led‑5159659801312477137170
viny3203674801315174133180
zůstává34086748013154113153189240288339
jednou3772674801313386148207267326
z41236748013154
nejvyšších42016748013169123146196250291332354403462
v46886748013159
rámci4772674801314192183233256
urolo‑50526748013168100158182242277
gických3203689801316082130175227274332
malignit.35636898013190139161182242299321354373
Incidence3960689801312785134155215267325374425
RCC44136898013155117175
neustále46166898013159112169209243293315368
stoupá,5008689801314579135193253303321
na32037048013159108
čem33357048013158108198
se36017048013150103
jistě372870480131325493127178
podílí39317048013169128189211235257
i42127048013131
zvýšený42677048013153106158199252310356
záchyt46477048013153104153211257294
inciden‑4966704801313189137159219272330363
tálních3203719801313484106163185233291
nálezů35227198013159108130183227285
na38367198013159107
ledvinách3967719801312881141191213271320368426
u44217198013159
asymptomatických4504719801315494143233293326382471520552574623668720767825
pacientů32037348013162113163185239299331390
při36187348013170103126
provádění37697348013171104162211262323377436459
zobrazovacích42537348013153111173206257303361410461511534583642
vyšetření49207348013159112154208242275327387409
z32037498013144
jiné3271749801313254111164
indikace.3459749801313189148170215266315366383
Většina38667498013164115148189210268317
nálezů42077498013167116138191235293
jsou4524749801313271129187
tumory47357498013142100189247279331
malé,50987498013190139161214231
nicméně3203764801315980128217270328380
nezanedbatelnou36047648013158111156206264317377436486518568591648706764
porci43887648013161120151198220
tvoří4632764801313082139170192
lokálně4848764801312078124174196254306
po‑51747648013161120155