Ces Urol 2018, 22(4):285-290 | DOI: 10.48095/cccu2018046

A case report of a patient with a renal carcinoma and metachronously affected bilateral adrenal glands and her contralatral kidney over a period of 16 years

Petr Klézl1, Kateřina Licková2, Jindřich Šonský1, Aleš Fiala1, Petr Nencka1, Robert Grill1
1 Urologická klinika FN Královské Vinohrady a 3. LF UK Praha
2 Onkologická klinika FN Královské Vinohrady a 3. LF UK Praha

Klézl P, Licková K, Šonský J, Fiala A, Nencka P, Grill P. A case report of a patient with a renal carcinoma and metachronously affected bilateral adrenal glands and her contralatral kidney over a period of 16 years. We present a case report of a 64 years old female patient with renal carcinoma and metachronic metastases to the contralateral kidney, subcutaneous tissue and both adrenals glands during a course of 16 years after primary nephrectomy. Renal carcinoma metastases occur after several years most often in the area of the lungs, lymph nodes and the liver. At the time of diagnosis, approximately 25 % of patients have a generalized disease. The occurrence of metastases is dependent on the histological type, grade and size of the tumor. Bilateral metastases in the adrenal gland and the contralateral kidney are a challenge in the diagnosis and treatment of the disease because there are standard defined procedures for the treatment of these patients in the literature. We repeatedly used surgery because it seemed the most optimal solution in view of the development of the disease and the condition of the patient.

Keywords: Renal carcinoma, metachronous metastases, nephrectomy.

Received: September 1, 2018; Accepted: November 14, 2018; Prepublished online: November 14, 2018; Published: December 1, 2018 


References

  1. Novák J, Stolz J, Babjuk M, Hanuš T, Jarolím T. Léčba generalizovaného karcinomu ledviny. Ces Urol 2001; 3: 40-43.
  2. Patard JJ, Leray E, Rioux‑Leclercq N, et al. Prognostic value of histological subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol 2005; 23(12): 2763-2771. Go to original source... Go to PubMed...
  3. Sobotka R, Hanuš T. Nádory ledvin. Postgraduální medicína 2011: 1.
  4. Kawaciuk I. Prognóza karcinomu ledviny. Praha: Galén 2005.
  5. Leibovich BC, Blute ML, Cheville JC, et al. Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: a stratification tool for prospective clinical trials. Cancer 2003; 97(7): 1663-1671. Go to original source... Go to PubMed...
  6. Mesurolle B, Mignon F, Travagli JP, Meingan P, Vanel D. Late presentation of solitay contralateral adrenal metastasis of renal cell carcinoma. Eur Radiol 1997; 7: 557-558. Go to original source... Go to PubMed...
  7. Kuczyk M, Münch T, Machtens S, et al. The need for routine adrenalectomy during surgical treatment for renal cell cancer: the Hannover experience. BJU Int. 2002; 89: 517-522. Go to original source... Go to PubMed...
  8. Kobayashi T, Nakamura E, Yamamoto S, et al. Low incidence of ipsilateral adrenal involvement and recurrences in patients with renal cell carcinoma undergoing radical nephrectomy: a retrospective analysis of 393 patients. Urology 2003; 62: 40-45. Go to original source... Go to PubMed...
  9. Alt AL, Boorjian SA, Lohse CM, et al. Survival after complete surgical resection of multiple metastases from renal cell carcinoma. Cancer 2011; 117: 2873-2882. Go to original source... Go to PubMed...
  10. Yu CC, Huang JK, Tzeng WS, et al. Simultaneous bilateral adrenal metastases from renal cell carcinoma. Surgical implications and review of the literature. Eur Urol. 1992; 22: 335-338. Go to original source... Go to PubMed...
  11. Karam JA, Wood CG. The role of surgery in advanced renal cell carcinoma: cytoreductive nephrectomy and metastasectomy. Hematol Oncol Clin North Am. 2011; 25: 753-764. Go to original source... Go to PubMed...
  12. Kessler OJ, Mukamel E, Weinstein R, et al. Metachronous renal cell carcinoma metastasis to the contralateral adrenal gland. Urology 1998; 51: 539-543. Go to original source... Go to PubMed...
  13. Becker F, Siemer S, Tzavaras A, Suttmann H, Stoeckle M. Long‑term survival in bilateral renal cell carcinoma: a retrospective single‑institutional analysis of 101 patients after surgical treatment. Urology 2008; 72: 349-353. Go to original source... Go to PubMed...
  14. Boorjian SA, Crispen PL, Lohse CM, Leibovich BC, Blute ML. The impact of temporal presentation on clinical and pathological outcomes for patients with sporadic bilateral renal masses. Eur. Urol. 2008; 54: 855-865. Go to original source... Go to PubMed...





Web časopisu Česká urologie je určen pouze pro lékaře a odborníky
z oblasti medicíny nebo farmacie.



Beru na vědomí, že informace zveřejněné na těchto stránkách
nejsou určeny pro laickou veřejnost.



Odejít Vstoupit