Ces Urol 2020, 24(1):69-73 | DOI: 10.48095/cccu2020008

Case report of a gigantic recurrent angiomyolipoma in a horseshoe kidney

Markéta Hulová, Michal Staník, Daniel Macík, Jan Doležel
Oddělení urologické onkologie, Masarykův onkologický ústav, Brno

We present a case report of gigantic recurrent angiomyolipoma of the horseshoe kidney in a young patient with suspected tuberous sclerosis syndrome. The condition was solved by repeated cytoreductive surgery in combination of systemic treatment with mTOR inhibitors.

Keywords: Angiomyolipoma, tuberous sclerosis, horseshoe kidney, mTOR inhibitor.………

Received: January 30, 2020; Revised: February 13, 2020; Accepted: February 13, 2020; Prepublished online: February 16, 2020; Published: March 19, 2020 


References

  1. Flum AS, Hamoui N, Said MA, et al. Update on the Diagnosis and Management of Renal Angiomyolipoma. J Urol 2016; 195: 834-846. Go to original source... Go to PubMed...
  2. Ürge T, Pitra T, Chudáček Z, et al. Nové trendy v léčbě renálního angiomyolipomu. Ces Urol 2015; 19(2): 106-117.
  3. Fernández‑Pello S, Hora M, Kuusk T, et al. Management of sporadic renal angiomyolipomas: a systematic review of available evidence to guide recommendations from the European Association of Urology renal cell carcinoma guidelines panel. Eur Urol Oncol 2019 Jun 3. pii: S2588-9311(19)30054-9.
  4. Paldus V, Šámal V, Mečl J, et al. Wunderlichův syndrom - soubor pacientů s netraumatickým spontánním krvácením do retroperitonea. Ces Urol 2019; 23: 230-236.
  5. Hušek P, Košina J, Pacovský J, et al. Roboticky asistovaná resekce objemného angiomyolipomu levé ledviny. Ces Urol 2018; 22: 234-237.
  6. Samuels JA. Treatment of renal angiomyolipoma and other hamartomas in patients with tuberous sclerosis complex. Clin J Am Soc Nephrol 2017; 12: 1196-1202. Go to original source... Go to PubMed...
  7. Bhatt JR, Richard PO, Kim NS, et al. Natural history of renal angiomyolipoma (AML): most patients with large AMLs >4 cm can be offered active surveillance as an initial management strategy. Eur Urol 2016; 70: 85-90. Go to original source... Go to PubMed...
  8. McCormack FX, Inoue Y, Moss J, et al. Efficacy and safety of sirolimus in lymphangioleiomyomatosis. N Engl J Med 2011; 364: 1595-1606. Go to original source... Go to PubMed...
  9. Bissler JJ, Kingswood JC, Radzikowska E, et al. Everolimus long‑term use in patients with tuberous sclerosis complex: four‑year update of the EXIST-2 study. PLoS One 2017; 12: e0180939. Go to original source...
  10. Toriu N, Mizuno H, Sawa N, et al. Everolimus reduces the size of tuberous sclerosis complex‑related huge renal angiomyolipomas exceeding 20 cm in the longest diameter. Case Rep Oncol 2018; 11: 258-267. Go to original source... Go to PubMed...





Web časopisu Česká urologie je určen pouze pro lékaře a odborníky
z oblasti medicíny nebo farmacie.



Beru na vědomí, že informace zveřejněné na těchto stránkách
nejsou určeny pro laickou veřejnost.



Odejít Vstoupit