Ces Urol 2001, 5(3):40-43 | DOI: 10.48095/cccu2001030
Treatment of the generalized renal carcinoma
- Urologická klinika 1. LF UK a VFN, Praha
A group of 1498 patients with RCC was treated. From this group 86 patients were primarily generalized. For the treatment of primary advanced metastasis the treatment strategy was changed from conservative to an active approach. The basis for this approach is the removal of 75 % of the tumor mass, good condition of the patient, no metastatic site in CNS, bone and liver, and the primary tumour should not be a sarcoma. The new treatment strategy for patients with advanced RCC is a combination of surgery and chemoimmunotherapy as the standard treatment. 47 patients from our group were tretaed with combined INF alfa+ IL-2 + 5 FU + isotretinoin using the Atzpodien scheme. The toxicity was minimal and by 6 patients who underwent treatment had a disease progression. The results with this treatment strategy are encouraging, but we recommend further randomized trials.
Keywords: Renal cell carcinoma, Surgery, Chemotherapy, Immunotherapy
Published: June 1, 2001
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