Ces Urol 2005, 9(3):13-15 | DOI: 10.48095/cccu2005015
Use of porcine small intestinal submucosa graft in anterior urethral strictures reconstruction
- Urologická klinika FN Olomouc
Aim: Skin and mucosal grafts or skin flaps are used for surgical reconstructions in patients with anterior urethral strictures. Their use is accompanied with increased morbidity from donor site or from flap development. SIS is acellular heterologous matrix available as a potential tissue substitution for urethral reconstructions. Our study addresses the role of SIS in this indication.
Materials and methods: We have performed the operation in 7 patients with bulbar, 2 with bulbopenile and 2 with distal penile urethral stricture including meatus and fossa navicularis. SIS was used as an onlay patch in all patients.
Results: Clinical, cosmetic and radiologic results were excellent in 10 patients during the mean follow-up 17.2 months. A short relapse of stricture was observed only in 1 patient. No complications, such as fistulas, wound infections, urinary infections or rejection, were seen.
Conclusion: The use of SIS appears to be a promising method for primary urethral reconstructions in patients with anterior urethral strictures.
Keywords: urethral stricture, urethral reconstruction, matrix
Published: June 1, 2005
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