Ces Urol 2012, 16(4):214-221 | DOI: 10.48095/cccu2012036

The use of molecular genetics in the differential diagnosis of renal tumors

Jindřich Branžovský1, Petr Martínek1, Kevin Baulet1, Ivan Trávníček2, Petr Stránský2, Tomáš Vaněček1, Milan Hora2, Ondřej Hes1
1 Šiklův patologicko-anatomický ústav LF UK a FN, Plzeň
2 Urologická klinika LF UK a FN, Plzeň

Renal tumors are a highly heterogenous group of tumors which makes their diagnosis increasingly complicated. The use of molecular and genetic techniques has resulted not only in the improvement of classification and differential diagnosis, but has also led to a better understanding of the biological behavior of these tumors. The increasing use of targeted therapy makes precise diagnosis of each lesion important and in the future it may become a crucial tool for the selection of proper treatment.

Keywords: kidney, renal cell carcinoma, oncocytoma, translocation renal cell carcinoma, morphology, molecular biology, diagnostics, genetics, biological treatment, differential diagnostics

Received: August 4, 2012; Accepted: November 22, 2012; Published: September 1, 2012 

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