Ces Urol 2026, 30(3):137-141 | DOI: 10.48095/cccu2026023

Procedural pain and anxiety during flexible uretrocystoscopy in men - a comparative study of a group of patients with and without local application of an anesthetic gel to the urethra

Hana Ochtinská1, Marcel Janda2, David Brebera3
1 Katedra ošetřovatelství, Fakulta zdravotnických studií, Univerzita Pardubice
2 Urologie, Pardubická nemocnice, Nemocnice Pardubického kraje a.s.
3 Katedra informatiky a matematiky v dopravě, Dopravní fakulta Jana Pernera, Univerzita Pardubice
53 2 10 Pardubice hana.ochtinska@upce.cz

Major statement: Flexible urethrocystoscopy is an important tool in urology. To reduce pain, an anesthetic gel is administered before the procedure. However, there are discussions about its necessity in foreign studies. The aim of the article is to present data obtained from Czech men and evaluate their subjective perception of pain and anxiety during the examination.

Summary
Aim: To determine the perception of the intensity of procedural pain and anxiety in men undergoing diagnostic flexible urethrocystoscopy.

Material and methods: The analysis included 135 patients divided into two groups – 70 men who received 2% lidocaine gel applied to the external urethral orifice before flexible urethrocystoscopy and 65 men who did not receive this local anesthetic gel. Respondents rated the subjective level of procedural pain and anxiety at selected stages of the examination using a numerical scale of 0–10.

Result: The analysis showed that patients without the application of a local anesthetic gel perceived lower pain intensity both during the procedure (1.4 without gel vs. 1.97 with gel; P = 0.047) and after its completion (0.8 without gel vs. 1.374 with gel; P = 0.014) compared to the group with local anesthetic gel application. In all monitored variables, patients without local anesthetic gel also had lower levels of anxiety, which gradually decreased in individual phases of the examination (2.2 vs. 1.9; P = 0.360; 1.8 vs. 1.4; P = 0.072; 0.8 vs. 0.5; P = 0.115), but the differences were not statistically significant. It was also found that older patients correlated with lower sensitivity to pain and anxiety (age–pain during examination R = –0.251; age–anxiety during examination R = –0.356). The results also indicate that the patient's psychological state significantly influences their perception of pain, especially during local anesthetic gel application.

Conclusion: Although further research is needed, the results of our study did not demonstrate the benefit of applying a local anesthetic gel in reducing subjectively perceived pain and anxiety during diagnostic flexible urethrocystoscopy.

Keywords: flexible urethrocystoscopy – procedural pain – subjective assessment – anxiety

Received: April 11, 2026; Revised: July 12, 2026; Accepted: September 2, 2026; Published: September 21, 2026 


References

  1. McClintock G, Wong E, Mancuso P. Music during flexible cystoscopy for pain and anxiety - a patient-blinded randomised control trial. BJU Int 2021; 128(Suppl 1): 27-32. doi: 10.1111/bju.15527. Go to original source... Go to PubMed...
  2. Gupta S, Das SK, Jan D et al. Distraction during cystoscopy to reduce pain and increase satisfaction: Randomized control study between real-time visualization versus listening to music versus combined music and real-time visualization. Urol Ann 2019; 11(1): 33-38. doi: 10.4103/UA.UA_191_17. Go to original source... Go to PubMed...
  3. Wuilleumier J, Point D, Fooks H et al. The history of cystoscopy in urology. Int J Urol 2016; 14(1). doi: 10.5580/IJU.26400. Go to original source...
  4. Cano-Garcia MC, Casares-Perez R, Arrabal-Martin M et al. Use of Lidocaine 2% gel does not reduce pain during flexible cystoscopy and is not cost-effective. Urol J 2015; 12(5): 2362-2365.
  5. Laszkiewicz J, Krajewski W, Luczak M et al. Pain reduction methods during transurethral cystoskopy. Contemp Oncol 2021; 25(2): 80-87. doi: 10.5114/wo.2021.106652. Go to original source... Go to PubMed...
  6. Carrion A, García-Cruz E, Fernandez C et al. Previous urethral lubrication does not reduce pain perception in men undergoing flexible cystoscopy. Urol Int 2016; 97(4): 392-396. doi: 10.1159/000447497. Go to original source... Go to PubMed...
  7. Khalil S, Taha S, Al-Nesf M. Correlation between skin test results and historical manifestations in patients with suspected lidocaine hypersensitivity. Qatar Med J 2022; 2022(2): 16. doi: 10.5339/QMJ.2022.FQAC.16. Go to original source...
  8. Safiullah S, Lama DJ, Patel R et al. Procedural module: flexible cystoscopy. J Endourol 2018; 32(Suppl 1): S2-S6. doi: 10.1089/end.2017.0706. Go to original source...
  9. Gradwell L, Pietropaolo A. Reducing UTI and sepsis after flexible cystoscopy: impact of a protocol-based approach in high-risk patients-outcomes from a high-volume university teaching hospital. Oncologist 2025; 30(Suppl 1): oyaf248.026. doi: 10.1093/oncolo/oyaf248.026. Go to original source...
  10. Akkoç A, Kartalmiş M, Aydin C et al. 2% Lidocaine gel or plain lubricating gel: Which one should be used in male flexible cystoscopy? Turk J Urol 2016; 42(2): 92-96. doi: 10.5152/tud.2016.18784. Go to original source... Go to PubMed...
  11. Myles PS, Myles DB, Gallaher W et al. Measuring acute postoperative pain using the visual analog scale: the minimal clinically important difference and patient acceptable symptom state. Br J Anaesthesia 2017; 118(3): 424-429. doi: 10.1093/bja/aew466. Go to original source... Go to PubMed...
  12. Öztürk E, Yikilmaz TN, Hamidi N et al. Scheduled or immediate cystoscopy: Which option reduces pain and anxiety? Int Urol Nephrol 2023; 55(1): 37-41. doi: 10.1007/s11255-022-03364-5. Go to original source...
  13. Biardeau X, Lam O, Ba V et al. Prospective evaluation of anxiety, pain, and embarrassment associated with cystoscopy and urodynamic testing in clinical practice. Can Urol Assoc J 2017; 11(3-4): 104-110. doi: 10.5489/CUAJ.4127. Go to original source... Go to PubMed...





Web časopisu Česká urologie je určen pouze pro lékaře a odborníky
z oblasti medicíny nebo farmacie.



Beru na vědomí, že informace zveřejněné na těchto stránkách
nejsou určeny pro laickou veřejnost.



Odejít Vstoupit