Ces Urol 2000, 4(2):30-32 | DOI: 10.48095/cccu2000011

Renal oncocytoma - tumor of unambiguous benignity

M. Hora1, Z. Ouda1, O. Hes2, M. Michal2, M. Roušarová3
Fakultní nemocnice Plzeň
1 Urologická klinika
2 Šiklův patologicko-anatomický ústav
3 Národní onkologický registr

Renal oncocytoma (M8290/1) represents about 5 % of all renal tumors. Former literature repetitively mentioned the possibility of its malignant development. The update knowledge document that so called metastatic oncocytomas were probably chromophobe renal cell carcinomas or granular forms of clear cell renal carcinoma with incorrect histology classification. The correct histology diagnosis has the crucial significance.
In the time period from 1992 to 3/1999 the number of 15 patients underwent surgery for oncocytoma at the Urology Department of the Faculty Hospital in Plzeň (representing 4,82 % from the total number of 311 renal tumor operations). 8 patients were male and 7 were female, the average age was 67,6 ?6,0 years.
Patients survive without symptoms of oncocytoma's generalization or some have died for different reasons.
This study certifies the classification of renal oncocytoma as benign tumor. Authors conclude that in such cases is the perfect differential diagnostics of the pathologist crucial.

Keywords: Renal tumors, Oncocytoma, Benignity, Histopathology

Published: March 1, 2000 


References

  1. Amin M. B., Crotty T.B., Tickoo S.K., Farrow G.M.: Renal oncocytoma: a reappraisal of morpho-logic features with clinicopathological findings in 80 cases, Am. J. Surg. Pathol., 1997, 21(1); s. 1-12 Go to original source... Go to PubMed...
  2. Barnes A., Beckman E.N.: Renal oncocytoma and its congeners, Am. J. Clin. Pathol., 1983, 79; 312-318 Go to original source... Go to PubMed...
  3. Baše J.: Bilaterální multifokální onkocytomy ledviny, Rozhl. Chir., 75, 1996; s. 573-575
  4. Bonsib S.M., Bromley Ch: Immunocytochemical analysis of band 3 protein in renal cell carcinoma, nephroblastoma, and oncocytoma, Arch. Pathol. Lab. Med., 1994, 118; s. 702-704
  5. Dechet Ch.B., Bostwick D.G., Blute M.L. et al.: Renal Oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma, J. Urol., 1999, 162; s. 40-42 Go to original source... Go to PubMed...
  6. Dijkhuizen T. van den Berg E., Störkel S. et al.: Renal oncocytoma with t(5;12;11), DER (1)t(1;8) and ADD (19): "true" oncocytoma or chromophobe adenoma?, Int. J. Cancer, 1997, 73; s. 521-524 Go to original source... Go to PubMed...
  7. Hanuš T., Novák J., Petřík R., Voska L.: Renální onkocytom, Rozhl. Chir., 76, 1997; s. 530-533
  8. Hes O., Michal M., Skálová A.: Renal oncocytomas with Hale's colloidal iron-positive cytoplasm, J. Urol. Pathol., 1997, 7; s. 177-187
  9. Hora M., Hes O.: Histologie nádorů ledvin dospělých, Čes. Urol., 5/1998, 2; s. 2932
  10. Hora M., Ouda Z., Schejbalová E. et al.: Histologické nálezy u nádorů ledvin, Rozhl. Chir., 1/1997, 76; s. 9-16
  11. Kostakopulos A., Stavropoulos N.J.: Renal oncocytoma: managenent and treatment, Eur. Urol. Update Ser., 2/1995, 4; 10 s.
  12. Kovacz G., Szücs S., Eichner W. et al.: Renal oncocytoma - a cytogenetic and morphologicla study, Cancer, 1987, 59; s. 2071-2077 Go to original source... Go to PubMed...
  13. Lieber M.M., Tomera K.M., Farrow G.M.: Renal oncocytoma, J. Urol., 1981, 125; s. 481-485 Go to original source... Go to PubMed...
  14. Morell-Quadreny L., Gregori-Romero M.A., Carda-Batalla C., Llombart-Bosch A.: Renal oncocy-tomas (typical and atypical variants), Int. J. Surg. Pathol., 1996, 3(4); s. 219-228 Go to original source...
  15. Perez-Ordonez B., Hamed G., Campbell S. et al.: Renal oncocytoma: a clinicopathologic study of 70 cases, Am. J. Surg. Pathol., 1997, 21(8); s. 871-883 Go to original source... Go to PubMed...
  16. Störkel S., Eble JN, Adlakha K et al.: Classification of renal cell carcinoma, Cancer, 5/1997, 80; s. 987-989 Go to original source...
  17. Tickoo S.K., Amin M.B.: Disciriminant nuclear features of renal oncocytoma and chromophobe renal cell carcinoma, Am. J. Clin. Pathol., 1998, 110; s. 782-787 Go to original source... Go to PubMed...
  18. Val-Bernal J.F., Gonzáles-Vela C., Gómez J., Acebo E.: Unilateral simultaneous renal cell carci-noma and oncocytoma, letters to the editor, Am. J. Surg. Pathol., 1998, 22(2); s. 271-272 Go to original source... Go to PubMed...
  19. Wereich G., Glenn G., Junker K. et al.: Familial renal oncocytoma: clinicopathological study of 5 families, J. Urol., 1998, 160; s. 335-340 Go to original source... Go to PubMed...
  20. Wu T., Bihrle R., Yum M.N.: Heterotopic adrenal cortical adenoma masquerading as metastatic renal cell carcinoma, J. Urol., 2/1999, 161; s. 595-596 Go to original source...
  21. Záťura F., Fiala R., Študent V. et al.: Onkocytom ledviny jako příčina výrazné anémie, Čes. Urol., 1/1998, 2; s. 16-17





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